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Optimal Treatment Strategies for use of Anti-Obesity Medications (AOMs) in Children and Adolescents Research Coordinating Center (U24 Clinical Trial Not Allowed)

National Institutes of Health · Diabetes, Digestive, and Kidney Diseases Extramural Research (93.847)

Publicada 8 jun 2026 · Cierra mañana

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Resumen aún no disponible en español; se muestra en inglés.

The US National Institutes of Health funds a Research Coordinating Center to lead a consortium testing anti-obesity medication strategies in children and adolescents, evaluating optimal timing, dosing, and adjunct therapies. Only US-based organisations including non-profits, universities, businesses, and government agencies may apply, with applications due by 9 October 2026.

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Resumen

Texto original del donante (inglés)

This Notice of Funding Opportunity (NOFO) invites applications for a Research Coordinating Center (RCC) to participate in a consortium of clinical centers that will test anti-obesity medication (AOM) treatment strategies for youth with obesity that maximize benefits and minimize risks of AOM use. Such intervention strategies should support the promotion of healthy growth and development; adequate nutritional status/intake, healthy eating and physical activity behaviors; mental health and well-being (e.g., body image, self-esteem, mood, etc.), and quality of life and be feasible to implement in clinical care settings. Priority areas include testing strategies to determine optimal developmental stage for AOM initiation, rate and amount of weight loss, AOM class, dose, frequency, and duration, and content and intensity of adjunct lifestyle therapies that may be imperative to ensure normal psychological and physical development and to potentially avoid lifelong dependence on AOMs. Investigators should also evaluate potential predictors of response/ nonresponse to various treatment strategies under evaluation. The clinical centers may conduct independent or multicenter trials but will…

Extracto de la página del donante. El texto completo, los anexos y los formularios están en la convocatoria original.

Quién puede presentar una solicitud

  • ONG / sociedad civil
  • Institución académica o de investigación
  • Empresa privada
  • Organismo gubernamental
  • Organización comunitaria

Elegibilidad y condiciones

Mostrar el texto de elegibilidad de la fuente · Texto original del donante (inglés)

Applicant types: Private institutions of higher education; For profit organizations other than small businesses; Native American tribal governments (Federally recognized); Special district governments; Independent school districts; State governments; Public housing authorities/Indian housing authorities; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; City or township governments; Native American tribal organizations (other than Federally recognized tribal governments); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; County governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); Public and State controlled institutions of higher education

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/Foreign Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

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