Development of Biomarkers or Composite Biomarkers for Neurological and Neuromuscular Disorders (R61/R33 - Clinical Trial Optional)
National Institutes of Health · Extramural Research Programs in the Neurosciences and Neurological Disorders (93.853)
Publicada 28 oct 2024 · Quedan aproximadamente 15 meses
En pocas palabras
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The US National Institutes of Health funds research to identify and evaluate biomarkers for neurological and neuromuscular disorders, with preliminary human studies required alongside animal work. Only US-based organisations—universities, nonprofits, government bodies, and businesses—may apply, with applications due by 7 January 2028.
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Resumen
Texto original del donante (inglés)
The overarching purpose of this Funding Opportunity Announcement (FOA) is to promote the discovery and/or early evaluation of strong candidate biomarkers and biomarker signatures that can be used as tools to facilitate the clinical development of neurotherapeutics and their use in clinical practice. Specifically, the focus of this FOA is on the identification and initial biological, analytical and clinical evaluation of biomarkers and biomarker signatures for neurological and neuromuscular disorders. Although research supported by this FOA can include animal studies, it must also include preliminary human evaluation using carefully standardized human samples or datasets. The goal of this initiative is to deliver candidate biomarkers or biomarker signatures that are ready for definitive analytical and clinical validation studies.
Extracto de la página del donante. El texto completo, los anexos y los formularios están en la convocatoria original.
Quién puede presentar una solicitud
- Institución académica o de investigación
- ONG / sociedad civil
- Empresa privada
- Organismo gubernamental
Elegibilidad y condiciones
Mostrar el texto de elegibilidad de la fuente · Texto original del donante (inglés)
Applicant types: County governments; Public and State controlled institutions of higher education; Independent school districts; Small businesses; Native American tribal organizations (other than Federally recognized tribal governments); Others (see text field entitled "Additional Information on Eligibility" for clarification); Public housing authorities/Indian housing authorities; For profit organizations other than small businesses; City or township governments; State governments; Special district governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; Native American tribal governments (Federally recognized)
Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.
Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.