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Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Development and Validation of Model Systems to Facilitate Neurotherapeutic Discovery (R61/R33 Clinical Trial Not Allowed)

National Institutes of Health · Extramural Research Programs in the Neurosciences and Neurological Disorders (93.853)

Publicada 22 oct 2024 · Quedan aproximadamente 13 meses

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Resumen aún no disponible en español; se muestra en inglés.

The National Institutes of Health funds development and validation of animal models and tissue systems to advance neurological and neuromuscular disorder research, with grants up to 750,000 US dollars for early translational work. Foreign organisations and US entities are eligible; applications are due by 20 October 2027.

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Resumen

Texto original del donante (inglés)

This funding opportunity announcement (FOA) encourages the development and validation of animal models and human/animal tissue ex vivo systems that recapitulate the phenotypic and physiologic characteristics of a defined neurological or neuromuscular disorder. The goal of this FOA is to promote a significant improvement in the translational relevance of animal models or ex vivo systems that will be utilized to facilitate future development of neurotherapeutics. Ideally, models proposed for this FOA would have the potential to provide feasible and meaningful assessments of efficacy following therapeutic intervention that would be applicable in both preclinical and clinical settings. This FOA is part of a suite of Innovation Grants to Nurture Initial Translational Efforts (IGNITE) Program focused on enabling the exploratory and early stages of drug discovery.

Extracto de la página del donante. El texto completo, los anexos y los formularios están en la convocatoria original.

Quién puede presentar una solicitud

  • Institución académica o de investigación
  • Empresa privada
  • ONG / sociedad civil
  • Organismo gubernamental
  • Empresa social o cooperativa

Elegibilidad y condiciones

Mostrar el texto de elegibilidad de la fuente · Texto original del donante (inglés)

Applicant types: Small businesses; State governments; County governments; Native American tribal governments (Federally recognized); Private institutions of higher education; Public and State controlled institutions of higher education; City or township governments; For profit organizations other than small businesses; Native American tribal organizations (other than Federally recognized tribal governments); Public housing authorities/Indian housing authorities; Independent school districts; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Special district governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education

Other Eligible Applicants include the following:

Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

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