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Mechanistic Evaluation of Therapeutic Targets derived from Treatable Traits to Improve CNS Outcomes in People with HIV (R21/R33 Clinical Trial Not Allowed)

National Institutes of Health · Mental Health Research Grants (93.242)

Publicada 30 sept 2026 · Quedan aproximadamente 13 meses

En pocas palabras

Resumen aún no disponible en español; se muestra en inglés.

The U.S. National Institutes of Health funds research to identify and validate therapeutic targets for HIV-associated central nervous system complications using innovative models. Eligible U.S. organizations include nonprofits, universities, governments, and small businesses; the deadline is 28 October 2027 and applications must be in English.

Un resumen generado del texto del donante; la redacción original figura más abajo.

Resumen

Texto original del donante (inglés)

The purpose of this notice of funding opportunity (NOFO) is to identify modifiable mechanisms and therapeutic targets to address central nervous system (CNS) complications associated with human immunodeficiency virus (HIV). The initiative supports a phased research approach beginning with the identification of patient phenotypes characterized by convergent pathophysiological features, followed by the discovery and experimental validation of molecular mechanisms using innovative in-vitro and in-vivo models. The goal of this NOFO is to advance therapeutic target, and intervention discovery to address the multifactorial and heterogeneous nature of HIV-associated CNS dysfunction.

Extracto de la página del donante. El texto completo, los anexos y los formularios están en la convocatoria original.

Quién puede presentar una solicitud

  • Organismo gubernamental
  • ONG / sociedad civil
  • Institución académica o de investigación
  • Empresa privada

Elegibilidad y condiciones

Mostrar el texto de elegibilidad de la fuente · Texto original del donante (inglés)

Applicant types: City or township governments; Private institutions of higher education; Public and State controlled institutions of higher education; Native American tribal governments (Federally recognized); Native American tribal organizations (other than Federally recognized tribal governments); Small businesses; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; State governments; County governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; For profit organizations other than small businesses; Special district governments; Public housing authorities/Indian housing authorities; Others (see text field entitled "Additional Information on Eligibility" for clarification); Independent school districts

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

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