NCCIH Natural Product Mid Phase Clinical Trial (R01 Clinical Trial Required)
National Institutes of Health · Research and Training in Complementary and Integrative Health (93.213)
Publié 2 déc. 2024 · 36 jours restants
En clair
Résumé pas encore disponible en français ; affiché en anglais.
The National Institutes of Health funds mid-phase clinical trials of natural products such as botanicals, dietary supplements, and probiotics that show promise in treating health conditions. Applicants must be based in the United States, include universities, nonprofits, small businesses, and government entities, and submit applications in English by 13 November 2026.
Un résumé généré du texte du bailleur ; la formulation originale figure ci-dessous.
Résumé
Texte original du bailleur (anglais)
This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated mid-phase clinical trials of natural products(i.e., botanicals, dietary supplements, and probiotics), which have a strong scientific premise to justify further clinical testing. For this NOFO, natural products include promising nutritional regimens that standardize the amount of a specific naturally occurring nutritional compound (e.g., omega-3 fatty acids, anthocyanidins, or polyphenols) and have compelling preliminary evidence. All applications submitted under this NOFO must be supported by sufficient preliminary data demonstrating bioavailability (if applicable) and documentation that the natural product produces a reproducible and measurable impact on target engagement (i.e., measure of the mechanism of action). Only in cases when it is not possible/practical to measure target engagement in the patient population of interest or when there is a fundamental understanding of the products mechanism of action will this preliminary data requirement be waived.
Applications submitted to this NOFO should propose a mid-phase clinical trial to do the following: determine the optimal dose or…
Extrait de la page du bailleur. Le texte intégral, les annexes et les formulaires se trouvent dans l'appel original.
Qui peut candidater
- Établissement universitaire ou de recherche
- Organisme public
- Entreprise privée
- ONG / société civile
- Organisation communautaire
Éligibilité et conditions
Afficher le texte d'éligibilité de la source · Texte original du bailleur (anglais)
Applicant types: City or township governments; State governments; Public housing authorities/Indian housing authorities; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; Small businesses; For profit organizations other than small businesses; County governments; Public and State controlled institutions of higher education; Independent school districts; Native American tribal governments (Federally recognized); Special district governments; Native American tribal organizations (other than Federally recognized tribal governments); Others (see text field entitled "Additional Information on Eligibility" for clarification)
Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.
Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.