Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics (R01 Clinical Trial Optional)
National Institutes of Health · Cancer Cause and Prevention Research (93.393)
Publié 18 nov. 2024 · Environ 3 mois restants
En clair
Résumé pas encore disponible en français ; affiché en anglais.
The US National Institutes of Health funds preclinical and clinical research examining how incretin-mimetic drugs (GLP-1, GIP-1, and dual agents) affect cancer risk, welcoming researchers from universities, nonprofits, government agencies, and other eligible institutions globally. Applications in English are due by 7 January 2027.
Un résumé généré du texte du bailleur ; la formulation originale figure ci-dessous.
Résumé
Texte original du bailleur (anglais)
The goal of the proposed funding announcement is twofold, to promote preclinical and patient based studies examining the mechanism(s) through which incretin mimetics (including agonists or antagonists of GLP-1, GIP-1, or dual GLP-1/GIP-1 agents) impact cancer risk, and to draw talented scientists who understand the dynamic changes caused by these agents to investigate the mechanisms of how these agents influence cancer risk rather than shorter term outcomes such as weight loss and diabetes. The data thus far suggests that these agents may increase the risk of some, while decreasing the risk of other obesity related cancers.
Extrait de la page du bailleur. Le texte intégral, les annexes et les formulaires se trouvent dans l'appel original.
Régions éligibles
- Monde entier
Qui peut candidater
- Organisme public
- Établissement universitaire ou de recherche
- Entreprise privée
- ONG / société civile
- Organisation communautaire
Éligibilité et conditions
Afficher le texte d'éligibilité de la source · Texte original du bailleur (anglais)
Applicant types: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Private institutions of higher education; For profit organizations other than small businesses; Small businesses; Special district governments; County governments; Public and State controlled institutions of higher education; City or township governments; Native American tribal organizations (other than Federally recognized tribal governments); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; State governments; Independent school districts; Public housing authorities/Indian housing authorities; Native American tribal governments (Federally recognized)
Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.