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Clinical Characterization of Cancer Therapy-induced Adverse Sequelae and Mechanism-based Interventional Strategies (R01 Clinical Trial Optional)

National Institutes of Health · Cancer Cause and Prevention Research (93.393)

Publié 6 nov. 2024 · Environ 15 mois restants

En clair

Résumé pas encore disponible en français ; affiché en anglais.

The National Institutes of Health funds research projects that investigate how to prevent or reduce long-term side effects from cancer treatments, including basic research, clinical studies, and development of new therapeutic approaches. Eligible applicants include US and foreign non-profits, universities, government bodies, and small businesses, with applications due by 7 January 2028.

Un résumé généré du texte du bailleur ; la formulation originale figure ci-dessous.

Résumé

Texte original du bailleur (anglais)

The purpose of this Funding Opportunity Announcement (FOA) is to support collaborative research projects designed to address adverse sequelae of cancer therapies that persist and become chronic comorbidities or develop as delayed posttreatment effects. This FOA supports basic, translational, and clinical research projects that seek to identify the mechanisms of therapy-induced adverse sequelae, clinically characterize the adverse sequelae, or translate the mechanistic understanding into therapeutic approaches to prevent or minimize the development of long-term sequelae. Research projects should focus on mechanistic studies with translational endpoints and longitudinal clinical phenotyping to identify and validate clinical endpoints (biomarkers, imaging, patient-reported outcomes, or combined elements) for future use in clinical trials that will evaluate the efficacy of interventions designed to prevent or reduce specific adverse sequelae.

Extrait de la page du bailleur. Le texte intégral, les annexes et les formulaires se trouvent dans l'appel original.

Qui peut candidater

  • ONG / société civile
  • Établissement universitaire ou de recherche
  • Entreprise privée
  • Organisme public

Éligibilité et conditions

Afficher le texte d'éligibilité de la source · Texte original du bailleur (anglais)

Applicant types: For profit organizations other than small businesses; State governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); Native American tribal governments (Federally recognized); County governments; Public housing authorities/Indian housing authorities; Special district governments; Native American tribal organizations (other than Federally recognized tribal governments); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; City or township governments; Private institutions of higher education; Public and State controlled institutions of higher education; Independent school districts; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education

Other Eligible Applicants include the following:

Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Thèmes