Revision Applications for Validation of Biomarker Assays Developed Through NIH-Supported Research Grants (R01 Clinical Trial Not Allowed)
National Institutes of Health · Cancer Detection and Diagnosis Research (93.394)
Опубликован 10 окт. 2024 г. · Осталось 6 дней
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The US National Institutes of Health funds research to validate cancer biomarker assays developed with prior NIH support, including clinical validation using specimens from trials and cohorts. The programme accepts applications from US government bodies, nonprofits, universities, small businesses, and foreign organisations, with applications due by 14 October 2026.
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Исходный текст донора (английский)
Through this Notice of Funding Opportunity (NOFO) is to accelerate the pace of translation of NCI-supported methods/assays/technologies (referred to as "assays") to the clinic. Specifically, the focus of this NOFO is on the adaption and clinical validation of molecular/cellular/imaging markers (referred to as "markers" r "biomarkers") for cancer detection, diagnosis, prognosis, monitoring, and prediction of response in treatment, as well as markers for cancer control and prevention. Research applications may support the acquisition of well-annotated specimens from NCI-supported or other clinical trials or observational cohorts/consortia for the purpose of clinical validation of the assay. Research projects proposed for this NOFO encourage multi-disciplinary interaction among scientific investigators, assay developers, clinicians, statisticians, and clinical laboratory staff. Clinical laboratory scientist(s) and statistical experts are highly encouraged to comprise integral parts of the application. This NOFO is not intended to support early-stage development of technology or the conduct of clinical trials, but rather the adaption and validation of assays to the point where they…
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Кто может подать заявку
- Государственный орган
- НКО / гражданское общество
- Академическое или исследовательское учреждение
- Частная компания
- Организация местного сообщества
- Агентство ООН или межправительственная организация
Требования и условия
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Applicant types: County governments; Independent school districts; State governments; Native American tribal organizations (other than Federally recognized tribal governments); Private institutions of higher education; Special district governments; City or township governments; Public housing authorities/Indian housing authorities; For profit organizations other than small businesses; Small businesses; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Public and State controlled institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Native American tribal governments (Federally recognized); Others (see text field entitled "Additional Information on Eligibility" for clarification)
Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.