Glioblastoma Therapeutics Network (GTN) (U19 Clinical Trial Required)
National Institutes of Health · Cancer Detection and Diagnosis Research (93.394)
Posted 31 Aug 2026 · Closes tomorrow
In plain terms
The National Cancer Institute funds research teams developing novel therapies for adult glioblastoma that can cross the blood-brain barrier and testing them in early clinical trials, with awards up to 700,000 US dollars. Only U.S. organisations including nonprofits, universities, governments and companies may apply, with the next deadline on 1 October 2026.
A generated summary of the donor's text; the original wording is below.
Summary
Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) solicits applications for research on novel therapies for adult glioblastoma (GBM). The goal is to improve the treatment of adult GBM by developing novel effective agents that can cross the blood brain barrier (BBB) and testing them clinically. Successful early-stage trials of new drugs from this NOFO would transition seamlessly to later stage trials using well-established NCI clinical trial mechanisms.To implement this concept, a highly collaborative GBM Therapeutics Network (GTN) of cross-cutting teams will be established, each team capable of driving therapeutic agent(s) from pre-clinical development, through investigational new drugs (IND) studies, into pilot clinical studies in humans. Appropriate therapeutic agents include: (1) novel agents or (2) agents or combinations approved for other indications and repurposed for treatment of GBM following appropriate preclinical studies. The scope of the NOFO, from late pre-clinical through early (Phase 0/1) clinical studies, uniquely spans a gap in the GBM drug development process.
Excerpt from the donor's page. The full text, annexes and forms are on the original call.
Who can apply
- ngo_cso
- academia_research
- private_company
- government
- community_based_org
Eligibility and conditions
Show the eligibility text from the source
Applicant types: Special district governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); Native American tribal organizations (other than Federally recognized tribal governments); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Public and State controlled institutions of higher education; Independent school districts; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Public housing authorities/Indian housing authorities; For profit organizations other than small businesses; Native American tribal governments (Federally recognized); Small businesses; City or township governments; Private institutions of higher education; State governments; County governments
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.