Glioblastoma Therapeutics Network (GTN) (U19 Clinical Trial Required)
National Institutes of Health · Cancer Detection and Diagnosis Research (93.394)
Publicada 31 ago 2026 · Quedan aproximadamente 3 meses
En pocas palabras
Resumen aún no disponible en español; se muestra en inglés.
The National Cancer Institute funds research teams developing novel therapies for adult glioblastoma that can cross the blood-brain barrier and testing them in early clinical trials, with awards up to 700,000 US dollars. Only U.S. organisations including nonprofits, universities, governments and companies may apply, with the next deadline on 1 October 2026.
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Resumen
Texto original del donante (inglés)
Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) solicits applications for research on novel therapies for adult glioblastoma (GBM). The goal is to improve the treatment of adult GBM by developing novel effective agents that can cross the blood brain barrier (BBB) and testing them clinically. Successful early-stage trials of new drugs from this NOFO would transition seamlessly to later stage trials using well-established NCI clinical trial mechanisms.
To implement this concept, a highly collaborative GBM Therapeutics Network (GTN) of cross-cutting teams will be established, each team capable of driving therapeutic agent(s) from pre-clinical development, through investigational new drugs (IND) studies, into pilot clinical studies in humans. Appropriate therapeutic agents include: (1) novel agents or (2) agents or combinations approved for other indications and repurposed for treatment of GBM following appropriate preclinical studies. The scope of the NOFO, from late pre-clinical through early (Phase 0/1) clinical studies, uniquely spans a gap in the GBM drug development process.
Extracto de la página del donante. El texto completo, los anexos y los formularios están en la convocatoria original.
Quién puede presentar una solicitud
- ONG / sociedad civil
- Institución académica o de investigación
- Empresa privada
- Organismo gubernamental
- Organización comunitaria
Elegibilidad y condiciones
Mostrar el texto de elegibilidad de la fuente · Texto original del donante (inglés)
Applicant types: Native American tribal organizations (other than Federally recognized tribal governments); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Public and State controlled institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Special district governments; City or township governments; State governments; Public housing authorities/Indian housing authorities; Private institutions of higher education; County governments; Native American tribal governments (Federally recognized); Independent school districts; Small businesses; For profit organizations other than small businesses
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.