Translational Bioinformatics and Experimental Approaches to Advance Drug Repositioning and Combination Therapy Development for Alzheimers Disease and Related Dementias (R01 Clinical Trial Not Allowed)
National Institutes of Health · Aging Research (93.866)
Publicada 30 dic 2024 · Quedan aproximadamente 19 meses
En pocas palabras
Resumen aún no disponible en español; se muestra en inglés.
The National Institutes of Health funds research using mouse models to test existing and investigational drugs for Alzheimer's disease and related dementias, including drug combinations and combination with non-pharmacologic interventions. Grants up to 1,000,000 US dollars are available to nonprofits, universities, governments, and for-profit organizations (including foreign entities), with applications in English due by 7 May 2028.
Un resumen generado del texto del donante; la redacción original figura más abajo.
Resumen
Texto original del donante (inglés)
This Notice of Funding Opportunity (NOFO) invites applications that propose to use mouse models to conduct rigorous preclinical testing of drugs or drug combinations currently used for other conditions, as well as investigational drugs at various stages of clinical development, predicted to be efficacious in AD/ADRD. This initiative will also support preclinical testing of repurposable or investigational drug candidates in combination with non-pharmacologic interventions leading to robust translational outcomes. The central goal is to establish robust proof of concept that will enable rational drug repurposing and combination therapy development for the treatment and prevention of AD/ADRD.
Extracto de la página del donante. El texto completo, los anexos y los formularios están en la convocatoria original.
Regiones elegibles
- Todo el mundo
Quién puede presentar una solicitud
- ONG / sociedad civil
- Institución académica o de investigación
- Empresa privada
- Organismo gubernamental
Elegibilidad y condiciones
Mostrar el texto de elegibilidad de la fuente · Texto original del donante (inglés)
Applicant types: Independent school districts; For profit organizations other than small businesses; Private institutions of higher education; City or township governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); State governments; Public and State controlled institutions of higher education; Special district governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; Native American tribal governments (Federally recognized); Native American tribal organizations (other than Federally recognized tribal governments); County governments; Public housing authorities/Indian housing authorities; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.