Translational Bioinformatics and Experimental Approaches to Advance Drug Repositioning and Combination Therapy Development for Alzheimers Disease and Related Dementias (R01 Clinical Trial Not Allowed)
National Institutes of Health · Aging Research (93.866)
Publié 30 déc. 2024 · Environ 19 mois restants
En clair
Résumé pas encore disponible en français ; affiché en anglais.
The National Institutes of Health funds research using mouse models to test existing and investigational drugs for Alzheimer's disease and related dementias, including drug combinations and combination with non-pharmacologic interventions. Grants up to 1,000,000 US dollars are available to nonprofits, universities, governments, and for-profit organizations (including foreign entities), with applications in English due by 7 May 2028.
Un résumé généré du texte du bailleur ; la formulation originale figure ci-dessous.
Résumé
Texte original du bailleur (anglais)
This Notice of Funding Opportunity (NOFO) invites applications that propose to use mouse models to conduct rigorous preclinical testing of drugs or drug combinations currently used for other conditions, as well as investigational drugs at various stages of clinical development, predicted to be efficacious in AD/ADRD. This initiative will also support preclinical testing of repurposable or investigational drug candidates in combination with non-pharmacologic interventions leading to robust translational outcomes. The central goal is to establish robust proof of concept that will enable rational drug repurposing and combination therapy development for the treatment and prevention of AD/ADRD.
Extrait de la page du bailleur. Le texte intégral, les annexes et les formulaires se trouvent dans l'appel original.
Régions éligibles
- Monde entier
Qui peut candidater
- ONG / société civile
- Établissement universitaire ou de recherche
- Entreprise privée
- Organisme public
Éligibilité et conditions
Afficher le texte d'éligibilité de la source · Texte original du bailleur (anglais)
Applicant types: Independent school districts; For profit organizations other than small businesses; Private institutions of higher education; City or township governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); State governments; Public and State controlled institutions of higher education; Special district governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; Native American tribal governments (Federally recognized); Native American tribal organizations (other than Federally recognized tribal governments); County governments; Public housing authorities/Indian housing authorities; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.