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Validation Center for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (U54 Clinical Trials Not Allowed)

National Institutes of Health · Trans-NIH Research Support (93.310)

Posted 30 Jun 2026 · Closes tomorrow

In plain terms

The US National Institutes of Health funds the creation of a Validation Center to evaluate AI-based clinical decision support tools that integrate medical imaging with multimodal health data for precision medicine. Applicants must be US-based institutions (universities, nonprofits, private companies, or government bodies), with awards up to 2 million US dollars, and applications are due by 2 October 2026.

A generated summary of the donor's text; the original wording is below.

Summary

The overarching goal of this notice of funding opportunity (NOFO) and its companion opportunities is to establish the Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) Program to support development of innovative, reliable, cost-effective, and sustainable multimodal AI-based clinical decision support (CDS) tools. PRIMED-AI CDS tools are based on the integration of clinical imaging with other types of multimodal health data to enhance care for patients with a wide range of health conditions. The PRIMED-AI Program seeks to catalyze the adoption of AI-based CDS tools into clinical workflows to enable novel personalized medicine strategies that address significant health challenges. The purpose of this NOFO is to solicit applications for the creation of a Validation Center to serve as a dedicated hub for the comprehensive evaluation and characterization of AI-enabled, image-based, multimodal CDS tools developed by the PRIMED-AI Consortium, to ensure these tools are reliable, reproducible, and generalizable. The Validation Center will focus on verification, validation, interoperability, and uncertainty quantification to comprehensively characterize…

Excerpt from the donor's page. The full text, annexes and forms are on the original call.

Who can apply

  • academia_research
  • ngo_cso
  • private_company
  • government
  • social_enterprise

Eligibility and conditions

Show the eligibility text from the source

Applicant types: Special district governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Public and State controlled institutions of higher education; Public housing authorities/Indian housing authorities; Small businesses; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; City or township governments; Private institutions of higher education; State governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); Independent school districts; Native American tribal organizations (other than Federally recognized tribal governments); Native American tribal governments (Federally recognized); For profit organizations other than small businesses; County governments

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

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