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Discovery of the Genetic Basis of Childhood Cancers and of Congenital Anomalies: Gabriella Miller Kids First Pediatric Research Program (X01 Clinical Trial Not Allowed)

National Institutes of Health · Trans-NIH Research Support (93.310)

Posted 18 Jun 2026 · About 3 months left

In plain terms

The US National Institutes of Health funds US research institutions to submit pediatric cancer and congenital anomaly samples for whole genome sequencing to advance understanding of genetic causes of childhood diseases. Applicants must be based in the United States, and applications are due by 11 January 2027; budget amounts are not specified in the call.

A generated summary of the donor's text; the original wording is below.

Summary

As part of the Gabriella Miller Kids First Pediatric Research Program (Kids First Program), the NIH invites applications to submit samples from pediatric cohorts for whole genome sequencing at a Kids First Program supported genomic data generating centers. Applicants are encouraged to propose sequencing of existing pediatric cancer or congenital anomaly cohorts to elucidate the genetic contribution (somatic and/or germline) to childhood cancers, to investigate the genetic etiology of congenital anomalies, to study the molecular basis of the associations between congenital anomalies and increased cancer risk, or to expand the range of pediatric disorders included within the Kids First Data Resource. The program will accept applications that propose whole genome, exome, and transcriptome sequencing, as well as clinical-grade sequencing, long-read sequencing, proteomics, and epigenomic assays of tumor or affected tissue, when justified. Applicants are encouraged to propose cohorts to increase representation of existing Kids First Program projects. These data, and associated clinical and phenotypic data, will become part of the Kids First Data Resource Center for sharing with the…

Excerpt from the donor's page. The full text, annexes and forms are on the original call.

Who can apply

  • academia_research
  • ngo_cso
  • private_company
  • government
  • community_based_org

Eligibility and conditions

Show the eligibility text from the source

Applicant types: Public housing authorities/Indian housing authorities; Independent school districts; Small businesses; Private institutions of higher education; For profit organizations other than small businesses; Native American tribal organizations (other than Federally recognized tribal governments); City or township governments; County governments; Special district governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; State governments; Public and State controlled institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Native American tribal governments (Federally recognized); Others (see text field entitled "Additional Information on Eligibility" for clarification)

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/Foreign CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

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