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The Genesis Mission: Transforming Science and Energy with AI

Office of Science · Office of Science Financial Assistance Program (81.049)

Posted 17 Mar 2026 · About 3 months left

In plain terms

The US Department of Energy Office of Science invites interdisciplinary teams to develop artificial intelligence models and workflows addressing energy, environmental, and nuclear challenges, with Phase I small-team grants from 500,000 to 16 million US dollars available. Applications in English are due by 17 December 2026.

A generated summary of the donor's text; the original wording is below.

Summary

The DOE Office of Science (SC), Office of Critical Minerals and Energy Innovation (CMEI), Office of Environmental Management (EM), Office of Nuclear Energy (NE), Office of Electricity (OE), and Hydrocarbons and Geothermal Office (HGEO) hereby announce interest in receiving applications from interdisciplinary teams addressing the Genesis Mission National Science and Technology Challenges to accelerate scientific discovery and research and development (R&D) workflows using novel artificial intelligence (AI) models and frameworks. By achieving AI advantage, these teams will advance the DOE's mission and ensure America’s security and prosperity by addressing energy, environmental, and nuclear challenges through science and technology. Teams are encouraged to leverage the extensive scientific and data resources of the DOE/National Nuclear Security Administration (NNSA), the National Laboratories, U.S. industry, and academia. The resulting AI models and workflows, if successful, may be integrated into the American Science Cloud.

DOE is soliciting new FY26 Phase I small team and Phase II large team applications in the following topic areas: advanced manufacturing, biotechnology, critical…

Excerpt from the donor's page. The full text, annexes and forms are on the original call.

Who can apply

  • ngo_cso
  • community_based_org
  • government
  • academia_research
  • private_company
  • social_enterprise
  • individual
  • un_agency
  • other

Eligibility and conditions

Show the eligibility text from the source

Applicant types: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility"

Countries

Themes