Development of Interventions to Prevent and Treat Substance Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional)
National Institutes of Health · Drug Use and Addiction Research Programs (93.279)
Posted 10 Sept 2025 · About 23 months left
Summary
The purpose of this Funding Opportunity (NOFO) is to solicit grant applications to support research on the discovery and development of interventions to prevent and/or treat substance use disorders (SUDs) and overdose, including medications and medical devices to treat co-morbid SUDs. This includes preclinical and clinical research studies that will have high impact and quickly yield the necessary results to advance candidate interventions closer to regulatory approval or clinical adoption. This NOFO will utilize the UG3/UH3 activity code.
Excerpt from the donor's page. The full text, annexes and forms are on the original call.
Eligibility and conditions
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Applicant types: Native American tribal governments (Federally recognized); Public and State controlled institutions of higher education; Public housing authorities/Indian housing authorities; For profit organizations other than small businesses; City or township governments; Special district governments; Small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Independent school districts; State governments; County governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Private institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments)
Other Eligible Applicants include the following:
Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; U.S. Territory or Possession.