Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics (R21 Clinical Trial Not Allowed)
National Institutes of Health · Cancer Cause and Prevention Research (93.393)
Posted 18 Nov 2024 · About 3 months left
In plain terms
The US National Institutes of Health funds preclinical and patient-based research examining how incretin-mimetic drugs (GLP-1, GIP-1, and dual agents) affect cancer risk in various populations. Multiple organisation types including nonprofits, universities, and foreign organisations may apply, with applications due by 7 January 2027.
A generated summary of the donor's text; the original wording is below.
Summary
The goal of the proposed funding announcement is twofold, to promote preclinical and patient based studies examining the mechanism(s) through which incretin mimetics (including agonists or antagonists of GLP-1, GIP-1, or dual GLP-1/GIP-1 agents) impact cancer risk, and to draw talented scientists who understand the dynamic changes caused by these agents to investigate the mechanisms of how these agents influence cancer risk rather than shorter term outcomes such as weight loss and diabetes. The data thus far suggests that these agents may increase the risk of some, while decreasing the risk of other obesity related cancers.
Excerpt from the donor's page. The full text, annexes and forms are on the original call.
Eligible regions
- global
Who can apply
- ngo_cso
- academia_research
- private_company
- government
- community_based_org
Eligibility and conditions
Show the eligibility text from the source
Applicant types: Native American tribal organizations (other than Federally recognized tribal governments); Independent school districts; Native American tribal governments (Federally recognized); State governments; Special district governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; For profit organizations other than small businesses; Small businesses; Public housing authorities/Indian housing authorities; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Public and State controlled institutions of higher education; County governments; City or township governments; Others (see text field entitled "Additional Information on Eligibility" for clarification)
Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.