Translational Centers Using Microphysiological Systems for Infectious Diseases (U54 Clinical Trial Not Allowed)
National Institutes of Health · Trans-NIH Research Support (93.310)
Publicada 20 oct 2026 · Quedan aproximadamente 3 meses
En pocas palabras
El objetivo de este aviso de oportunidad de financiación (NOFO) es apoyar a un consorcio de Centros Traslacionales que utilizan Sistemas Microfisiológicos (MPS) para Enfermedades Infecciosas (TCMID). Los esfuerzos recientes en el campo de los MPS se están orientando hacia la validación y el uso regulatorio, pero no se han centrado en modelos que estudien enfermedades infecciosas y la prueba de intervenciones médicas.
Resumen tomado del texto del donante, traducido automáticamente; la redacción original figura más abajo.
Resumen
Texto original del donante (inglés)
The purpose of this notice of funding opportunity (NOFO) is to support a consortium of Translational Centers using Microphysiological Systems (MPS) for Infectious Diseases (TCMID). Recent efforts in the MPS fields are moving towards validation and regulatory use but have not focused upon models studying infectious diseases and testing of medical interventions. The NIH and FDA have recently issued guidance and established initiatives for enhancing use of New Approach Methodologies (NAMs) in research and product development. This includes in vitro systems that allow scientists to model human disease and capture human variability and patient-specific characteristics that will accelerate safer treatments for patients while reducing costs and sparing use of laboratory animals. To meet this need, the Centers will refine well validated human tissue models studying infectious diseases to a level consistent with regulatory qualifications that will promote their adoption for use by product developers, supporting regulatory acceptance.
Extracto de la página del donante. El texto completo, los anexos y los formularios están en la convocatoria original.
Quién puede presentar una solicitud
- Organismo gubernamental
- ONG / sociedad civil
- Empresa privada
- Organización comunitaria
- Institución académica o de investigación
Elegibilidad y condiciones
Mostrar el texto de elegibilidad de la fuente · Texto original del donante (inglés)
Applicant types: Independent school districts; State governments; Public housing authorities/Indian housing authorities; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; For profit organizations other than small businesses; Native American tribal governments (Federally recognized); Native American tribal organizations (other than Federally recognized tribal governments); Others (see text field entitled "Additional Information on Eligibility" for clarification); Public and State controlled institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; City or township governments; Small businesses; Special district governments; County governments
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).