Translational Centers Using Microphysiological Systems for Infectious Diseases (U54 Clinical Trial Not Allowed)
National Institutes of Health · Trans-NIH Research Support (93.310)
Publié 20 oct. 2026 · Environ 3 mois restants
En clair
L'objectif de cet avis d'opportunité de financement (NOFO) est de soutenir un consortium de centres translationnels utilisant des systèmes microphysiologiques (MPS) pour les maladies infectieuses (TCMID). Les efforts récents dans le domaine des MPS évoluent vers la validation et l'utilisation réglementaire, mais ne se sont pas concentrés sur des modèles étudiant les maladies infectieuses et l'évaluation d'interventions médicales.
Résumé tiré du texte du bailleur, traduit automatiquement ; la formulation originale figure ci-dessous.
Résumé
Texte original du bailleur (anglais)
The purpose of this notice of funding opportunity (NOFO) is to support a consortium of Translational Centers using Microphysiological Systems (MPS) for Infectious Diseases (TCMID). Recent efforts in the MPS fields are moving towards validation and regulatory use but have not focused upon models studying infectious diseases and testing of medical interventions. The NIH and FDA have recently issued guidance and established initiatives for enhancing use of New Approach Methodologies (NAMs) in research and product development. This includes in vitro systems that allow scientists to model human disease and capture human variability and patient-specific characteristics that will accelerate safer treatments for patients while reducing costs and sparing use of laboratory animals. To meet this need, the Centers will refine well validated human tissue models studying infectious diseases to a level consistent with regulatory qualifications that will promote their adoption for use by product developers, supporting regulatory acceptance.
Extrait de la page du bailleur. Le texte intégral, les annexes et les formulaires se trouvent dans l'appel original.
Qui peut candidater
- Organisme public
- ONG / société civile
- Entreprise privée
- Organisation communautaire
- Établissement universitaire ou de recherche
Éligibilité et conditions
Afficher le texte d'éligibilité de la source · Texte original du bailleur (anglais)
Applicant types: Independent school districts; State governments; Public housing authorities/Indian housing authorities; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; For profit organizations other than small businesses; Native American tribal governments (Federally recognized); Native American tribal organizations (other than Federally recognized tribal governments); Others (see text field entitled "Additional Information on Eligibility" for clarification); Public and State controlled institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; City or township governments; Small businesses; Special district governments; County governments
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).